En gruppe lidelser og tilstander i hjernen som kan forårsake funksjonsforstyrrelser som karakteriseres av ulike previous av anfall, enten med eller uten innvirkning på bevisstheten, og med eller uten krampeanfall.

carbamazepine will lessen the extent or outcome of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.

In the event you miss out on a dose, get it once you recall. If it is nearly time on your future dose or near bedtime, skip the missed dose and only choose another dose. Usually do not choose double or further doses. Using a dose as well near to bedtime could ensure it is harder for you to rest.

Inhibition of platelet aggregation by clopidogrel is solely as a consequence of an active metabolite. Clopidogrel is metabolized to this active metabolite partly by CYP2C19. .

Ferraro et al (2005) examined the consequences of modafinil in vivo in rats and found that by alone it didn't boost serotonin transmission, nevertheless it did lead to a rise in effects of basic serotonin uptake inhibitors specified at sub threshold doses.

The US armed forces has successfully made use of modafinil to help helicopter pilots continue to be notify all through sustained operations.‍[nine]

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Norepinephrine: Modafinil raises The supply of norepinephrine, a stimulant neurotransmitter that promotes wakefulness and boosts alertness. The precise suggests by which modafinil accomplishes this improve is unclear.

modafinil will enhance the level or result of mavacamten by impacting hepatic enzyme CYP2C19 metabolism. Contraindicated. Robust or reasonable CYP2C19 inhibitors may increase mavacamten systemic exposure, resulting in heart failure because of systolic dysfunction.

modafinil will raise the stage or outcome of rabeprazole by influencing hepatic enzyme CYP2C19 metabolism. Insignificant/Significance Unidentified. Net effect on pantoprazole steps unknown as a consequence of opposing results of CYP450 enzymes; observe

Check Closely (one)voriconazole will improve the level or impact of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism.

tazemetostat will lower the level or outcome of modafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Watch.

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Shift get the job done problem, a ailment (generally in folks Doing work night, early early morning, or rotating shifts) involving difficulty sleeping when you need to and/or Serious sleepiness when you might want to be awake